Team AITM-Nepal: siRNA MEDIATED IMMUNE MODULATION FOR INNATE AND ADAPTIVE RESPONSE USING GENETICALLY ENGINEERED Escherichia coli

Team AHUT China: Shining Sanctifier Water, the origin of life, is the necessary and elementary component of our daily life. Various kinds of means have been developed to dispose nitrite and ammonium which are the main contaminants of this type of effluent. One of them is anaerobic ammonium oxidation bacteria (anammox) which can convert the fomite in the water into nitrogen. Our goal is to design a wastewater treatment system which can absorb the pollutant efficiently while transform it into luminous energy. We plan to use E.coli to design a bacterium that can digest the nitrite and ammonium in its interior using the disposal system from the anammox. Through the introduction of luciferase, the energy can be transformed into bioluminescence. Therefore, we named it Shining Sanctifier. This new star in synthetic biology will be applied to the sewage treatment system on a large scale while it can also be made into illuminating system.